The HUPO Human Proteome Project (HPP), a Global Health Research Collaboration

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Published: Sep 20, 2012
DOI: https://doi.org/10.5195/cajgh.2012.37

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Gilbert S. Omenn
University of Michigan

Abstract

The global Human Proteome Project (HPP) was announced by the Human Proteome Organization (HUPO) at the 2010 World Congress of Proteomics in Sydney, Australia, and launched at the 2011 World Congress of Proteomics in Geneva, Switzerland, with analogies to the highly successful Human Genome Project. Extensive progress was reported at the September 2012 World Congress in Boston, USA. The HPP is designed to map the entire human proteome using available and emerging technologies.

The HPP aims to create a molecular and biological foundation for improving health globally through better understanding of disease processes, more accurate diagnoses, and targets for more effective therapies and preventive interventions against many diseases. There are opportunities for individual investigators everywhere to access advanced datasets and to join HPP research teams.

Article Details

How to Cite
Omenn, G. S. (2012). The HUPO Human Proteome Project (HPP), a Global Health Research Collaboration. Central Asian Journal of Global Health, 1(1). https://doi.org/10.5195/cajgh.2012.37
Issue
Vol. 1 No. 1 (2012): Inaugural Issue
Section
Short Reports

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Revised 7/16/2018. Revision Description: Removed outdated link. 

Author Biography

Gilbert S. Omenn, University of Michigan

Director, Center for Computational Medicine & Bioinformatics
Professor of Internal Medicine, Human Genetics and Public Health

References

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Farrah T, Deutsch EW, Omenn GS, Campbell DS, Sun Z, Bletz JA, et al. A high-confidence human plasma proteome reference set with estimated concentrations in peptideatlas. Mol Cell Proteomics. 2011 Sep; 10(9):M110.006353. doi: 10.1074/mcp.M110.006353

Paik YK, Jeong SK, Omenn GS, Uhlen M, Hanash S, Cho SY, et al. The chromosome-centric Human Proteome Project for cataloging proteins encoded in the genome. Nat Biotechnol. 2012 Mar 7;30(3):221-223. doi: 10.1038/nbt.2152

Paik YK, Omenn GS, Uhlen M, Hanash S, Marko-Varga G, Aebersold R, et al. Standard guidelines for the chromosome-centric Human Proteome Project. J Proteome Res. 2012 Apr 6;11(4):2005-2013. doi: 10.1021/pr200824a