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Introduction: Depression is considered as one of the most serious health issues worldwide, and the search for the most effective and safe treatments for depression is essential. Aromatherapy with lavender have attracted the attention of many researchers due to their low cost and ease of use, so this study was conducted to review of the effects of aromatherapy with lavender essential oil on depression.
Methods: This systematic review study was conducted by searching the databases (SID, Magiran, Google-Scholar, Medline via PubMed, Scopus, and Web of Science) by using the keywords such as depression, Lavandula, Lavender, and Aromatherapy, as well as applying OR and AND operators to the end of January 1, 2020 A.D. The inclusion criteria were: 1) Interventional studies that determined keywords were in the title or keywords of the article, 2) aromatherapy was conducted through inhalation or massage, 3) the full text of paper was accessible, and 4) published in English or Persian. Finally, the information obtained from articles was extracted using a checklist.
Results: Out of 278 studies, 9 studies were included to the systematic review process after screening and eliminating duplicate papers according to the purpose of the study. Aromatherapy with lavender essential oil was conducted on the patients suffering from migraine, patients with the acute coronary syndrome, patients undergoing hemodialysis, community-dwelling older adult, and postpartum depression. The results obtained from some studies showed the positive effect of aromatherapy with lavender essential oil on depression whereas some studies did not report the effect of aromatherapy with lavender on depression significantly.
Conclusion: It seems that aromatherapy with lavender probably can be used as a complementary, simple, and inexpensive method to improve mild and moderate depression. It is recommended to earmark using a collaborative approach and make use of interdisciplinary and psychology specialists as well as complementary medicine in applying aromatherapy with lavender essential oil.
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James SL, Abate D, Abate KH, Abay SM, Abbafati C, Abbasi N, et al. Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. The Lancet. 2018;392(10159):1789-858.
Ali Montazeri, Seyed Javad Mousavi, Sepideh Omidvari, Mahmood Tavousi, Akram Hashemi, Tahereh Rostami. Depression in Iran: a systematic review of the literature (2000-2010). Health Monitor Journal of the Iranian Institute for Health Sciences Research. 2013;12(6):567-94.
Maurer DM. Screening for depression. American family physician. 2012;85(2):139-44.
Madsen IE, Nyberg ST, Hanson LM, Ferrie JE, Ahola K, Alfredsson L, et al. Job strain as a risk factor for clinical depression: systematic review and meta-analysis with additional individual participant data. Psychological medicine. 2017;47(8):1342-56.
Shi Y, Yang D, Zeng Y, Wu W. Risk factors for post-stroke depression: a meta-analysis. Frontiers in aging neuroscience. 2017;9:218-24.
Al Balawi MM, Faraj F, Al Anazi BD, Al Balawi DM. Prevalence of Depression and Its Associated Risk Factors among Young Adult Patients Attending the Primary Health Centers in Tabuk, Saudi Arabia. Open Access Macedonian Journal of Medical Sciences. 2019;7(17):2908-12.
Szczepańska-Gieracha J, Morka J, Kowalska J, Kustrzycki W, Rymaszewska J. The role of depressive and anxiety symptoms in the evaluation of cardiac rehabilitation efficacy after coronary artery bypass grafting surgery. European Journal of Cardio-Thoracic Surgery. 2012;42(5):e108-e14.
Ribeiro JD, Huang X, Fox KR, Franklin JC. Depression and hopelessness as risk factors for suicide ideation, attempts and death: meta-analysis of longitudinal studies. The British Journal of Psychiatry. 2018;212(5):279-86.
Olver JS, Hopwood MJ. Depression and physical illness. Medical Journal of Australia. 2013;199:9-12.
Katon W, Lin EH, Kroenke K. The association of depression and anxiety with medical symptom burden in patients with chronic medical illness. General hospital psychiatry. 2007;29(2):147-55.
Bao Y-P, Han Y, Ma J, Wang R-J, Shi L, Wang T-Y, et al. Cooccurrence and bidirectional prediction of sleep disturbances and depression in older adults: meta-analysis and systematic review. Neuroscience & Biobehavioral Reviews. 2017;75:257-73.
Raso V, Tolea MI, Casseb JSdR, Duarte AJdS, Greve JMDA. Depression is inversely associated with sexual satisfaction and physical function in men living with HIV/AIDS. MedicalExpress. 2016;3(6):158-65.
Kugler C, Meng M, Rehn E, Morshuis M, Gummert JF, Tigges-Limmer K. Sexual activity in patients with left ventricular assist devices and their partners: impact of the device on quality of life, anxiety and depression. European Journal of Cardio-Thoracic Surgery. 2018;53(4):799-806.
Wittmann M, Schreiber W, Landgrebe M, Hajak G. Circadian rhythms and depression. Fortschritte der Neurologie-Psychiatrie. 2018;86(5):308-18.
Habibzadeh H, Milan ZD, Radfar M, Alilu L, Cund A. Effects of peer-facilitated, video-based and combined peer-and-video education on anxiety among patients undergoing coronary angiography: randomised controlled trial. Sultan Qaboos University Medical Journal. 2018;18(1):e61-7.
Sharif F, Shoul A, Janati M, Kojuri J, Zare N. The effect of cardiac rehabilitation on anxiety and depression in patients undergoing cardiac bypass graft surgery in Iran. BMC cardiovascular disorders. 2012;12(1):40-6.
Unützer J, Klap R, Sturm R, Young AS, Marmon T, Shatkin J, et al. Mental disorders and the use of alternative medicine: results from a national survey. American Journal of Psychiatry. 2000;157(11):1851-7.
Cohen ZD, DeRubeis RJ. Treatment selection in depression. Annual Review of Clinical Psychology. 2018;14-9.
Akil H, Gordon J, Hen R, Javitch J, Mayberg H, McEwen B, et al. Treatment resistant depression: a multi-scale, systems biology approach. Neuroscience & Biobehavioral Reviews. 2018;84:272-88.
Ciasca EC, Ferreira RC, Santana CLA, Forlenza OV, Dos Santos GD, Brum PS, et al. Art therapy as an adjuvant treatment for depression in elderly women: a randomized controlled trial. Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999). 2018;40(3):256-63.
Petrovsky D, Cacchione PZ, George M. Review of the effect of music interventions on symptoms of anxiety and depression in older adults with mild dementia. Int Psychogeriatr. 2015;27(10):1661-70.
Costa F, Ockelford A, Hargreaves DJ. Does regular listening to preferred music have a beneficial effect on symptoms of depression and anxiety amongst older people in residential care? The qualitative findings of a mixed methods study. Music and Medicine. 2018;10(2):54-62.
Tang SK, Tse MYM. Aromatherapy: Does It Help to Relieve Pain, Depression, Anxiety, and Stress in Community-Dwelling Older Persons? BioMed Research International. 2014;2014:12-8.
Babakhanian M, Ghazanfarpour M, Kargarfard L, Roozbeh N, Darvish L, Khadivzadeh T, et al. Effect of Aromatherapy on the Treatment of Psychological Symptoms in Postmenopausal and Elderly Women: A Systematic Review and Meta-analysis. Journal of menopausal medicine. 2018;24(2):127-32.
Cooke B, Ernst E. Aromatherapy: a systematic review. Br J Gen Pract. 2000;50(455):493-6.
Maddocks‐Jennings W, Wilkinson JM. Aromatherapy practice in nursing: literature review. Journal of advanced nursing. 2004;48(1):93-103.
Bagheri-Nesami M, Shorofi SA, Nikkhah A, Espahbodi F. The effects of lavender essential oil aromatherapy on anxiety and depression in haemodialysis patients. Pharmaceutical and Biomedical Research. 2017;3(1):8-13.
Yaghoobi K, Kaka GR, Davoodi Sh, Ashayeri H. Therapeutic effects of Lavandula angustifolia. Journal of Gorgan University of Medical Sciences. 2015;17(4):1-9.
Bagheri-Nesami M, Espahbodi F, Nikkhah A, Shorofi SA, Charati JY. The effects of lavender aromatherapy on pain following needle insertion into a fistula in hemodialysis patients. Complementary therapies in clinical practice. 2014;20(1):1-4.
Ghods A, Abfroosh N, Ghorbani R, Asgari M. Effect of Lavender Inhalation on Pain Intensity during Insertion of Vascular Needles in Hemodialysis Patients. Journal of Babol University Of Medical Sciences. 2014;16(10):7-14.
Beyliklioğlu A, Arslan S. Effect of Lavender Oil on the Anxiety of Patients Before Breast Surgery. J Perianesth Nurs. 2019;34(3):587-93.
Franco L, Blanck TJJ, Dugan K, Kline R, Shanmugam G, Galotti A, et al. Both lavender fleur oil and unscented oil aromatherapy reduce preoperative anxiety in breast surgery patients: a randomized trial. J Clin Anesth. 2016;33:243–9.
Özkaraman A, Ö D, Yılmaz H. Aromatherapy: The effect of lavender on anxiety and sleep quality in patients treated with chemotherapy. Clinical journal of oncology nursing. 2018;22(2):203-10.
Cavanagh HM, Wilkinson JM. Biological activities of lavender essential oil. Phytother Res. 2002 Jun;16(4):301-8.
Bahrami T, Rejeh N, Heravi‐Karimooi M, Vaismoradi M, Tadrisi SD, Sieloff C. Effect of aromatherapy massage on anxiety, depression, and physiologic parameters in older patients with the acute coronary syndrome: A randomized clinical trial. International journal of nursing practice. 2017;23(6):e12601-6.
Janizadeh E, Badami R, Torkan A. Comparison of the Effectiveness of Yoga and Lavender on Symptoms of Depression in Elderly Women. J Res Behav Sci. 2016;14(4):421-7.
Kianpour M, Mansouri A, Mehrabi T, Asghari G. Effect of lavender scent inhalation on prevention of stress, anxiety and depression in the postpartum period. Iranian J Nursing Midwifery Res. 2016;21:197-201.
Kianpour M, Moshirenia F, Kheirabadi G, Asghari G, Dehghani A, Dehghani-tafti A. The effects of inhalation aromatherapy with rose and lavender at week 38 and postpartum period on postpartum depression in high-risk women referred to selected health centers of Yazd, Iran in 2015. Iranian. J Nursing Midwifery Res. 2018;23:395-401.
Tayebi A, Kasra Dehkordi A, Ebadi A, Sahraei H, Einollahi B. The Effect of Aromatherapy with Lavender Essential Oil on Depression, Anxiety and Stress in Hemodialysis Patients: A Clinical Trial. Journal of Evidence-Based Care. 2015;15(5):65-74.
Xiong M, Li Y, Tang P, Zhang Y, Cao M, Ni J, et al. Effectiveness of Aromatherapy Massage and Inhalation on Symptoms of Depression in Chinese Community-Dwelling Older Adults. The Journal of Alternative and Complementary Medicine. 2018;24(7):717-724.
Jafari-Koulaee A, Khenarinezhad F, Sharifi Razavi A, Bagheri-Nesami M. The Effect of Aromatherapy with Lavender Essence on Depression and Headache Disability in Migraine Patients: A Randomized Clinical Trial. Journal of Medicinal Plants. 2019;2(70):162-72.
Sehhatie F, Mirgafourvand M, Niri ZV. The effect of non-pharmaceutical methods of labor pain relief on mothers’ postpartum depression: a randomized controlled trial. International Journal of Women's Health and Reproduction Sciences. 2015;3(1):48-55.
Asar S, Jalalpour S, Ayoubi F, Rahmani M, Rezaeian M. PRISMA; preferred reporting items for systematic reviews and meta-analyses. Journal of Rafsanjan University of Medical Sciences. 2016;15(1):68-80.
Sayers A. Tips and tricks in performing a systematic review. The British Journal of General Practice. 2008;58(547):136-9.
Schardt C, Adams MB, Owens T, Keitz S, Fontelo P. Utilization of the PICO framework to improve searching PubMed for clinical questions. BMC Medical Informatics and Decision Making. 2007;7(1):1-6.
Jadad AR, Moore RA, Carroll D, Jenkinson C, Reynolds DJ, Gavaghan DJ, et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary? Controlled clinical trials. 1996;17(1):1-12.
Ali M, Oderuth E, Atchia I, Malviya A. The use of platelet-rich plasma in the treatment of greater trochanteric pain syndrome: a systematic literature review. J Hip Preserv Surg. 2018;5(3):209-19.
Fahimeh Sehhatie, Mozhgan Mirgafourvand, Zhaleh VN. The Effect of Non-Pharmaceutical Methods of Labor Pain Relief on Mothers’ Postpartum Depression: A Randomized Controlled Trial. International Journal of Women’s Health and Reproduction Sciences. 2015;3(1):48–55.
Wilkinson SM, Love SB, Westcombe AM, Gambles MA, Burgess CC, Cargill A, et al. Effectiveness of aromatherapy massage in the management of anxiety and depression in patients with cancer: a multicenter randomized controlled trial. Journal of Clinical Oncology. 2007;25(5):532-9.