@article{Felsenstein_Bira_Altanmircheg_Shonkuuz_Ochirpurev_Warburton_2020, title={Rapid Emergence of Multidrug-Resistance among Gram Negative Isolates at a Tertiary Pediatric and Maternity Hospital in Ulaanbaatar, Mongolia}, volume={9}, url={http://cajgh.pitt.edu/ojs/cajgh/article/view/371}, DOI={10.5195/cajgh.2020.371}, abstractNote={<div><p class="AbstractParagraphs"><strong>Introduction: </strong>Information on microbiological and susceptibility profiles of clinical isolates in Mongolia is scarce, hampering infection control and clinical care.</p><p class="AbstractParagraphs"><strong>Methods:</strong> Species and resistance profiles of 6334 clinical gram negative isolates, collected at Mongolia’s National Center for Maternal and Child Health between 2014 and 2017 were analyzed.</p><p class="AbstractParagraphs"><strong>Results:</strong> Annual proportion of multidrug-resistance among <em>E. coli </em>and <em>Enterobacter</em> isolates increased<em> </em>from 2.8% to 16.6% and 3.5% to 22.6% respectively; <em>Klebsiella </em>isolates exhibiting susceptibilities suggestive of extended spectrum beta-lactamase (ESBL) production from 73% to 94%. By 2017, 60.6% of <em>Klebsiella</em> isolates were multidrug-resistant, most originated from intensive care wards. <strong> </strong>Enterobacteriaceae exhibiting susceptibility patterns suggestive of ESBL production and multidrug-resistant organisms were common and their incidence increased rapidly.</p><p class="AbstractParagraphs"><strong>Conclusion:</strong> These findings will serve to build strategies to strengthen microbiological surveillance, diagnostics and infection control; and to develop empiric therapy and stewardship recommendations for Mongolia’s largest Children’s and Maternity hospital.</p></div>}, number={1}, journal={Central Asian Journal of Global Health}, author={Felsenstein, Susanna and Bira, Sarantsetseg and Altanmircheg, Narangerel and Shonkuuz, Enkhtur and Ochirpurev, Ariuntuya and Warburton, David}, year={2020}, month={Apr.} }